Characterization of the ionic liquid obtained by chlorosulfonation of 1-methylimidazole: 1-methyl-3-sulfonic acid imidazolium chloride, 1-methylimidazolium chlorosulfate or a zwitterionic salt? was written by Urban, Bela;Szalontai, Gabor;Papp, Mate;Feher, Csaba;Benyei, Attila C.;Skoda-Foldes, Rita. And the article was included in Journal of Molecular Liquids in 2021.Safety of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:
A great number of organic reactions catalyzed by the ionic liquid product of chlorosulfonation of 1-methylimidazole have been reported recently. At the same time controversial assumptions have appeared on the real structure of the catalyst. In the present report the primarily formed chlorosulfonation product is proved to be 1-methylimidazolium chlorosulfate ([HMim]+[SO3Cl]–) instead of 1-methyl-3-sulfonic acid imidazolium chloride, reported previously. The former structure is confirmed by X-ray crystallog. and NMR spectroscopy, including 1H-, 13C-, 17O- and 15N-1H HSQC measurements. 1H and 17O NMR experiments support fast hydrolysis of [HMim] [SO3Cl] resulting in the formation of [HMim][HSO4] in the presence of traces of water. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Safety of 1-Methyl-1H-imidazol-3-ium chloride).
1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Safety of 1-Methyl-1H-imidazol-3-ium chloride
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem