Diversification of imidazo[1,2-a]pyridines under microwave-assisted palladium-catalyzed Suzuki reaction was written by Lee, Jin-Hee;Park, Seung Yeong;Park, Areum;Yum, Eul Kgun. And the article was included in Journal of the Korean Chemical Society in 2017.Category: imidazoles-derivatives This article mentions the following:
Diversified synthesis of arylated imidazo[1,2-a]pyridines I [R = H, CF3, C6H5, 4-FC6H4; R1 = H, 5-(pyridin-4-yl), 6-(4-H3COC6H4), 7-C6H5, etc.; R2 = H, C6H5, 4-H3COC6H4, 2H-1,3-benzodioxol-5-yl, etc.] via microwave-assisted palladium-catalyzed Suzuki reaction of various bromoimidazo[1,2-a]pyridines II (X = H, 5-Br, 6-Br, 7-Br; Y = H, Br) with substituted arylboronic acids such as pyridin-4-ylboronic acid, (4-ethoxyphenyl)boronic acid, 2H-1,3-benzodioxol-5-ylboronic acid, etc. was described. In the experiment, the researchers used many compounds, for example, 5-Bromoimidazo[1,2-a]pyridine (cas: 69214-09-1Category: imidazoles-derivatives).
5-Bromoimidazo[1,2-a]pyridine (cas: 69214-09-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem