Acylation of benzimidazole by the Regel-Buechel method. 2. Deacylation and dissociation of 1-methyl-3-acyl-2-(1-methyl-2-benzimidazolyl)benzimidazolin-4-ones was written by Khristich, B. I.;Bondarenko, E. V.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1987.Application of 3012-80-4 This article mentions the following:
1-Methyl-3-acyl-2-(1-methylbenzimidazol-2-yl)-2-benzimidazolines with an excess of acyl halide are transformed to unstable 1-methyl-3-acyl-2-(1-methyl-3-acyl-2-benzimidazolin-2-yl)benzimidazolium chlorides, which undergo intramol. oxidation-reduction-decomposition to give 1,1′-dimethyl-2,2′-bibenzimidazolyl and aldehyde, and dissociates at the C-C bond connecting the benzimidazole and benzimidazoline fragments to a carbene-ylide and 1-methyl-3-acylbenzimidazolium chloride. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Application of 3012-80-4).
1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Application of 3012-80-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem