Kanzawa, Fumihiko et al. published their research in Chemical & Pharmaceutical Bulletin in 1971 | CAS: 26832-08-6

1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives

Inhibition of guanine deaminase with derivatives of imidazole was written by Kanzawa, Fumihiko;Hoshi, Akio;Kuretani, Kazuo. And the article was included in Chemical & Pharmaceutical Bulletin in 1971.Category: imidazoles-derivatives This article mentions the following:

Inhibition of guanine deaminase by derivatives of 5-amino-4-imidazole-carboxamide (I) was studied. The 5-chloro derivative (II) was the most inhibitory among the halogen derivatives, but was less effective than I. 4-Imidazolecarboximide (III) was the most potent inhibitor found, more active even than I. Imidazole itself was a weak inhibitor. The Et ester instead of the amide, and the 5-chloro-6-carboxamidoxime derivatives were less effective than I, and the 4,5-dicarboxylic acid derivative was almost inactive. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Category: imidazoles-derivatives).

1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem