The preparation and properties of partially protected 4-amino-1-methylimidazole-2-carboxylic acids to be used as intermediates in the synthesis of analogs of distamycin A was written by Grehn, Leif;Ding, Lu;Ragnarsson, Ulf. And the article was included in Acta Chemica Scandinavica in 1990.Name: Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate This article mentions the following:
Partially protected 4-amino-1-methylimidazole-2-carboxylic acid derivatives I (R = H, R1 = Et; R = CO2CMe3, R1 = H, CH2Ph; R = CHO, R1 = H) have been prepared by a convenient route from the nitro analog. I should serve as suitable precursors for the synthesis of oligoamides related to distamycin A. In addition, several intermediates and side-products have been characterized. In the experiment, the researchers used many compounds, for example, Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 109012-23-9Name: Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate).
Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 109012-23-9) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Name: Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem