Intermediates in the Dimroth rearrangement of imidazo[1,2-a]pyridines was written by Jacquier, Robert;Lopez, Helene;Maury, Georges. And the article was included in Journal of Heterocyclic Chemistry in 1973.SDS of cas: 25045-82-3 This article mentions the following:
Imidazo 1,2-a% pyridines, activated by a nitro group at position 6 or 8 undergo the Dimroth rearrangement in aqueous basic media. Intermediates of the rearrangement were detected and their structures investigated spectroscopically. In the experiment, the researchers used many compounds, for example, 6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3SDS of cas: 25045-82-3).
6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.SDS of cas: 25045-82-3
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem