Development of thermal dissociation atmospheric chemical ionization source for rapid mass spectrometric analysis of ambient samples was written by Han, Jing;Li, Jian-Qiang;Zhang, Xie;Hu, Bin;Luo, Ming-Biao;Chen, Huan-Wen. And the article was included in Fenxi Huaxue in 2011.Reference of 92507-97-6 This article mentions the following:
A novel thermal dissociation atm. chem. ionization source (TDCI) was developed for rapid chem. ionization of ambient analytes in complex matrixes. By coupling the TDCI source to a com. LTQ XL mass spectrometer, the dissociation of chem. reagents such as ionic liquids was systematically investigated using multiple-stage mass spectrometric experiments The primary ions generated through the thermal dissociation process of the ionic liquids were accelerated by the high voltage applied on the repelling electrode of the TDCI source, and then reacted with the analytes present in the matrixes of the raw samples to produce ions of analytes, which were then guided to the LTQ instrument for mass anal. The construction of the TDCI source was detailed in the text. The effects of the exptl. parameters such as the pyrolysis temperature, the distance, and the angles formed between the electrodes were exptl. studied using the signals of characteristic fragments of the ionic liquid Under the optimal exptl. parameters, TDCI was able to directly ionize a wide variety of compounds, including the poplar (e.g., amino acids, doping compounds) and non-polar chems. (e.g, naphthalene) for sensitive detection using LTQ-MS, without any sample pretreatment. The average time for a single sample anal. was less than 30s, and the relative standard deviation of the method was in the range of 5.9%-11.1%; and the LOD for naphthalene was estimated to be 2.93*10-7g/L. In the experiment, the researchers used many compounds, for example, 1-ethyl-2,3-dimethylimidazolium chloride (cas: 92507-97-6Reference of 92507-97-6).
1-ethyl-2,3-dimethylimidazolium chloride (cas: 92507-97-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Reference of 92507-97-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem