Verma, Raman K.’s team published research in Synthetic Communications in 43 | CAS: 4760-35-4

Synthetic Communications published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C4H3Cl2N3, Computed Properties of 4760-35-4.

Verma, Raman K. published the artcileDesign and Synthesis of Benzimidazole-Linked meta-Substituted Benzylidenes/Benzyls as Biologically Significant New Chemical Entities, Computed Properties of 4760-35-4, the publication is Synthetic Communications (2013), 43(14), 1882-1895, database is CAplus.

Meta-Linked thiazolidinedione (TZD)- and di-Et malonate (DEM)-based benzylidenes and Me acetoacetate (MAA)-based benzyl moieties linked to the 2-position of N-Me benzimidazole were synthesized. TZD- and DEM-based compounds were synthesized by condensation of 2,4-thiazolidinedone and DEM resp. with the corresponding 3-substituted benzaldehyde, whereas MAA-based compounds were obtained by halogen displacement with the corresponding 3-substituted phenol. These new chem. entities were designed to provide a balanced agonism at the peroxisome proliferator activated receptor alpha/gamma in the management of type 2 diabetes: a move from glitazones to selective PPAR modulators.

Synthetic Communications published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C4H3Cl2N3, Computed Properties of 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem