Gu, Yang published the artcileLigand-Controlled Copper-Catalyzed Highly Regioselective Difluoromethylation of Allylic Chlorides/Bromides and Propargyl Bromides, Product Details of C27H39ClN2, the publication is Chinese Journal of Chemistry (2018), 36(1), 55-58, database is CAplus.
Highly regiodivergent copper-catalyzed allylic/propargylic difluoromethylation reactions by employing different ligands were described. When 5,6-dimethyl-1,10-phenanthroline was used as the ligand, exclusively α-difluoromethylated products I [R = 4-ClC6H4, 4-CF3C6H4, 1-naphthyl, etc.] were obtained, while γ-selective difluoromethylated products II were generated when N-heterocyclic carbene-SIPr was used as the ligand. Likewise, α-difluoromethylated products III [Ar = 4-ClC6H4, 4-CF3C6H4, 4-t-BuC6H4, etc.] and γ-difluoromethylated products IV were achieved in the presence of similar copper catalysts for the reactions of propargyl bromides. Moreover, a copper-catalyzed asym. allylic difluoromethylation reaction with moderate to good enantioselectivity by the use of chiral ligands was afforded α-difluoromethylated products II [R = 3-ClC6H4, 4-CO2MeC6H4, 2,5-(Br)2C6H3, etc.].
Chinese Journal of Chemistry published new progress about 258278-25-0. 258278-25-0 belongs to imidazoles-derivatives, auxiliary class Achiral NHCs Ligands, name is 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, and the molecular formula is C27H39ClN2, Product Details of C27H39ClN2.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem