Zhao, Wangdan published the artcileDetermination and Thermodynamic Modeling of Solid-Liquid Phase Equilibrium for Esomeprazole Sodium in Monosolvents and in the (Ethanol + Ethyl Acetate) Binary Solvent Mixtures, Product Details of C17H18N3NaO3S, the publication is Journal of Chemical & Engineering Data (2017), 62(7), 1965-1972, database is CAplus.
Esomeprazole sodium was a proton pump inhibitor (PPI) synthesized using omeprazole sulfide. In this paper, we used a static-analytic method to analyze the solubility of our own synthesis of esomeprazole sodium in Et acetate, acetonitrile, Me iso-Bu ketone, ethanol, methanol, and in the (ethanol + Et acetate) mixtures between 278.15 and 328.15 K. A group of thermodn. models were selected such as the Jouyban-Acree equation, the modified Apelblat equation, and CNIBS/R-K equations. All equations can be well applied and the modified Apelblat equations are relatively better. We determined the thermodn. properties of esomeprazole sodium using the van’t Hoff equation furthermore, including the entropy, Gibbs energy, and enthalpy.
Journal of Chemical & Engineering Data published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C15H21BO3, Product Details of C17H18N3NaO3S.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem