Omar, Nabil M. published the artcileImproved spectrophotometric determination of antazoline, Recommanded Product: N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, the publication is Journal of Pharmaceutical Sciences (1978), 67(11), 1610-13, database is CAplus and MEDLINE.
A simple, precise, and accurate spectrophotometric determination of antazoline (I) salts was developed by improving the ceric sulfate procedure. Replacement of water with HOAc for the preparation of all assay solutions permitted reproducible measurements of the chromogen that absorbed at 505 nm. An appreciable increase in color stability was attained by the controlled addition of HClO4 to the ceric reagent prior to interaction with I at room temperature Evidence is provided to account for the oxidation of I at the expense of a complex ceric species. Other 2-imidazolines or phenylephrine did not interfere with the investigated color reaction. In addition to the high value of the chromogen molar absorptivity, ideal adherence of color absorption to Beer’s law permitted accurate and reproducible estimation of I over the 1-10-μg range. The procedure was applied to the anal. of different I dosage forms.
Journal of Pharmaceutical Sciences published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Recommanded Product: N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem