Melis-Decerf, C. published the artcileAn in vitro method simulating drug release from viscous eye drops in rabbit and man, Category: imidazoles-derivatives, the publication is Journal of Pharmacy and Pharmacology (1979), 31(1), 12-15, database is CAplus and MEDLINE.
The release of drugs from viscous solutions under conditions simulating the blinking movements in the rabbit and human eye was determined using a rotatable diffusion cell. For the solutions at rest, corresponding with the conditions at the surface of the rabbit cornea, the diffusion velocity decreased with increasing viscosity. When the solution was moved at a velocity corresponding to that of lacrimal fluid at the surface of the human eye, the influence of viscosity may be neglected.
Journal of Pharmacy and Pharmacology published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Category: imidazoles-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem