Chang, Jinyu published the artcilePreparation of 5-methyl-3,5-dipropyl-2-pyrazoline catalyzed by chloroaluminate ionic liquids, Safety of 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, the publication is Journal of Molecular Structure (2022), 132539, database is CAplus.
5-Methyl-3,5-dipropyl-2-pyrazoline is an intermediate for the preparation of new high energy fuels. In this paper, chloroaluminate ionic liquids ([Bmim]Cl-xAlCl3, x = 1, 1.2, 1.4, 1.6, 1.8, 2.0) were applied as green catalysts for the synthesis of 5-methyl-3,5-dipropyl-2-pyrazoline through the intramol. cyclization reaction of 2-pentyl ketazine. The effects of temperature, acidity and dosage of ionic liquids on the cyclization reaction were studied in detail and the highest catalytic performance was under the conditions as 110°, [Bmim]Cl-1.6AlCl3 and 10% of 2-pentyl ketazine. With the theor. simulations, the possible catalytic mechanism was proposed as the hydrogen-like interaction between Al ([Bmim]+AlCl4–) and N1 atoms, which increases the charge of N2 atoms, thereby improving its nucleophilicity and further making it undergo intramol. addition reaction with Me. This study will provide guidance for the green preparation of 5-methyl-3,5-dipropyl-2-pyrazoline.
Journal of Molecular Structure published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Safety of 3-Butyl-1-methyl-1H-imidazol-3-ium chloride.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem