Sung, Daekyung published the artcileFacile Method for Selective Immobilization of Biomolecules on Plastic Surfaces, HPLC of Formula: 359860-27-8, the publication is Langmuir (2009), 25(19), 11289-11294, database is CAplus and MEDLINE.
A key aspect of biochip and biosensor preparation is optimizing surface attachment of biomols. Here, the authors report a facile approach for selectively immobilizing biomols. on amphiphilic polymer-coated plastic surfaces with anti-biofouling properties. To modify plastic surfaces, the authors synthesized two types of random copolymers by radical polymerization, which consisted of three parts: an anchoring group; a PEG component, which acted as a repellent of nonspecific biomols.; and a functional group, to which biomols. were conjugated. Dodecyl- and benzyl-based copolymers were highly soluble in water, presumably due to the presence of multiple PEG groups, and could easily coat the model plastic surface (polystyrene) in an aqueous environment. The antibiofouling property of each polymer-coated plastic surface was examined by measuring the extent of nonspecific protein adsorption using bovine serum albumin (BSA). Both polymer-coated plastic surfaces showed a very low level of BSA adsorption relative to that of an uncoated plastic surface (control). Finally, the authors showed that streptavidin and antibodies, as representative biomols., could be selectively immobilized on the polymer-coated plastic surfaces imprinted with biotin and protein A, resp., by microcontact printing, exhibiting an intense signal with low background.
Langmuir published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C9H11BO4, HPLC of Formula: 359860-27-8.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem