Mazur, Elzbieta published the artcileEffect of histamine on tissue respiration of the cardiac muscle of rats treated with antihistaminics, Application of N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, the publication is Annales Universitatis Mariae Curie-Sklodowska, Sectio D: Medicina (1977), 273-80, database is CAplus and MEDLINE.
Incubation of rat myocardial slices with histamine-HCl (I-HCl) [23758-34-1] decreased O consumption by up to 67% after 45 min. Similar treatment of myocardial slices from rats pretreated with Diphergan [60-87-7] (30 mg/kg/day, i.p., for 7-10 days) resulted in only 43% inhibition at the end of 45 min. Pretreatment of rats with thenalidine calcium [67250-62-8] (25 mg/kg/day) or phenazoline-HCl [2508-72-7] (100 mg/kg/day) did not alter the effect of I on myocardial respiration.
Annales Universitatis Mariae Curie-Sklodowska, Sectio D: Medicina published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Application of N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem