Pec, Pavel published the artcileInhibition of pig kidney diamine oxidase by some 4,5-dihydroimidazole derivatives, Synthetic Route of 2508-72-7, the publication is Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium (1988), 91(Chem. 27), 227-34, database is CAplus.
The inhibitory activity of some physiol. interesting 4,5-dihydroimidazole derivatives on the activity of diamine oxidase (EC 1.4.3.6) was investigated. The enzyme was isolated from the cortex of pig kidney. Using 2-Me, 2-benzyl, (tolazoline), 2-N(4-tolyl)-N-(3-hydroxyphenyl)aminomethyl (phentolamine), 2-(1-naphthyl)methyl (naphazoline), 2-(2,6-dimethyl-4-tert-butylphenyl)methyl (xylometazoline) and 2-(N-phenyl-N-benzylamino)methyl (antazoline) 4,5-dihydro-imidazoles, the enzyme inhibition was noncompetitive in all cases. The Ki values were in the range 0.2-1.5 mM. The relations among inhibitor structure, Ki, and possible physiol. effects were discussed.
Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Synthetic Route of 2508-72-7.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem