Kankate, Rani S.’s team published research in Arabian Journal of Chemistry in 12 | CAS: 4760-35-4

Arabian Journal of Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, COA of Formula: C9H9ClN2.

Kankate, Rani S. published the artcileDesign, synthesis and antifungal evaluation of novel benzimidazole tertiary amine type of fluconazole analogues, COA of Formula: C9H9ClN2, the publication is Arabian Journal of Chemistry (2019), 12(8), 2224-2235, database is CAplus.

A novel series of compounds containing tertiary amine moiety, substituted benzimidazole and triazole ring I (X = Cl; R1 = Me, Et; R2 = Me, Ph) based on an initial design by mol. docking study of this scaffold at the active site of the fungal enzyme of lanosterol 14α-demethylase (homol. modeled of C. albicans) was synthesized by microwave irradiation The screening of the synthesized compounds for in vitro (turbidimetric method) and in vivo (kidney burden test) antifungal activity against C. albicans revealed activity for many compounds as comparable to that of fluconazole.

Arabian Journal of Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, COA of Formula: C9H9ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem