Novel one-pot facile synthesis of thiopyranopyrazole using [Hmim]HSO4 catalyst was written by Srivastava, Vishal;Singh, Pravin K.;Singh, Praveen P.. And the article was included in Croatica Chemica Acta in 2014.Category: imidazoles-derivatives The following contents are mentioned in the article:
An efficient and easy protocol has been developed for synthesis of thiopyranopyrazoles I (R = 4-ClC6H4, 4-MeOC6H4, 4-BrC6H4, etc.) by using [Hmim]HSO4 as recyclable catalyst under solvent-free condition at room temperature This environmentally benign method has advantages, such as high yield of products, simple work-up procedure, and avoidance of the organic solvents, which will contribute in serving as a green process greatly. The catalyst was easily recovered and reused without any considerable loss of activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem