Gastroprotective delivery of rabeprazole sodium along with metoclopramide hydrochloride using treated agar was written by Ratnakar, Raikar Prasiddhi;Pankaj, Gajare;Santoshi, Naik. And the article was included in International Journal of Pharmacy and Biological Sciences in 2021.Synthetic Route of C18H20N3NaO3S The following contents are mentioned in the article:
Particle engineering is a technique of phys. modification of the excipient at sub-particle level without altering chem. properties to achieve desired functionality. For development of immediate layer of Metoclopramide Hydrochloride Treated Agar was used as disintegrating agent and was compared with untreated agar. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6Synthetic Route of C18H20N3NaO3S).
Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Synthetic Route of C18H20N3NaO3S
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem