Effect of quadruple therapy on Hp eradication rate and gastrin level in patients with Helicobacter pylori-positive chronic superficial gastritis was written by Yan, Jin-he. And the article was included in Xiandai Zhenduan Yu Zhiliao in 2021.Application of 117976-90-6 The following contents are mentioned in the article:
Objective: To investigate the effect of quadruple therapy on Hp eradication rate and gastrin (GAS) level in patients with Helicobacter pylori (Hp) pos. chronic superficial gastritis. Methods: A total of 74 patients with Hp-pos. chronic superficial gastritis admitted to our hospital from August 2018 to Oct. 2019 were selected and divided into the control group and the observation group with 37 cases in each group according to the random number table method. The observation group was treated with rabeprazole sodium quadruple therapy, and the control group was treated with omeprazole quadruple therapy. After 6 wk of treatment, the Hp eradication rates, GAS levels and adverse reactions were compared between the two groups. Results: The eradication rate of Hp in the observation group was higher than that in the control group (P < 0.05). After 6 wk of treatment, the GAS levels in both groups were lower than those before treatment, and the observation group was significantly lower than the control group (P < 0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P < 0.05). Conclusion: Rabeprazole sodium quadruple therapy can improve Hp eradication rate and GAS level in Hp-pos. chronic superficial gastritis patients with good safety. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6Application of 117976-90-6).
Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Application of 117976-90-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem