Wang, Ting-Hsuan published the artcileNickel-Catalyzed Heteroarenes Cross Coupling via Tandem C-H/C-O Activation, Synthetic Route of 2622-67-5, the publication is ACS Catalysis (2018), 8(12), 11368-11376, database is CAplus.
Inert aryl Me ethers as coupling components via C-O activation have been established with a Ni catalyst for C-H activation of heteroarene. The key to simultaneous C-H/C-O bond activation is the use of sterically demanding o-tolylMgBr. The protocol is effective for a wide scope of substrates including naphthyl Me ethers, anisoles, and a variety of other heteroarene derivatives Detailed mechanistic studies indicated that the C-O cleavage is assisted via synergistic effect of nickel and Grignard reagent in this C-H/C-O reaction, which is supported by DFT calculation At this stage, single-electron transfer can be ruled out as a main operative process for this tandem strategy.
ACS Catalysis published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C8H4FNO3, Synthetic Route of 2622-67-5.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem