Kassem, A. A. published the artcileProlonged release antazoline hydrochloride tablets. Part 1. Using insoluble substances, Category: imidazoles-derivatives, the publication is Bulletin of the Faculty of Pharmacy (Cairo University) (1976), 14(1), 85-99, database is CAplus.
Addition of Mg stearate [557-04-0] and hydrogenated castor oil to antazoline-HCl (I) [2508-72-7] tablets made with Et cellulose [9004-57-3], prolonged the drug release. The tablets containing 15% and 20% Mg stearate released I more slowly in the gastric fluid than in the intestinal fluid, the release being more pronounced with the latter. Hydrogenated castor oil (10-20%) was perferred since it caused a gradual and uniform drug release both in gastric and intestinal fluids. Of the various retarding materials studied, hydrogenated castor oil caused the least erosion of I tablets, followed by Mg stearate.
Bulletin of the Faculty of Pharmacy (Cairo University) published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Category: imidazoles-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem