Kirk, Kenneth L. published the artcilePhotochemistry of diazonium salts. I. Synthesis of 4-fluoroimidazoles, 4-fluorohistamine, and 4-fluorohistidine, Related Products of imidazoles-derivatives, the main research area is photochem diazonium salt; fluorinated imidazole.
Imidazolediazonium ions, prepared by diazotization of aminoimidazoles in HBF4 and irradiated in situ, decompose with formation of fluoroimidazoles in 30-40% yield. 2-Fluoroimidazole, 4-fluoroimidazole, and Et 4-fluoroimidazole-5-carboxylate (I) were prepared I was the starting point for various transformations, including the synthesis of 4-fluorohistamine and 4-fluorohistidine. The fluorinated amino acid parallels histidine as a substrate for several enzymes and, in the case of histidine-ammonia lyase, serves as a competitive inhibitor.
Journal of the American Chemical Society published new progress about photochem diazonium salt; fluorinated imidazole. 30086-17-0 belongs to class imidazoles-derivatives, name is 5-Fluoro-1H-imidazole, and the molecular formula is C3H3FN2, Related Products of imidazoles-derivatives.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem