Freter, K. published the artcile4-(Indolyl-3)-1-(benzimidazolonylalkyl)piperidines, a novel group of potential antiallergy compounds, Quality Control of 52548-84-2, the main research area is benzimidazolone indolylpyridylalkyl antihistamine.
Antiallergic I (R1 = H, Me, Me2CH, R2 = H, Me, R3 = H, Me, isopropenyl, R5 = H, n = 2-6) were prepared in 34-92% yields by treating indole II with the corresponding N-(ω-chloroalkyl)benzimidazolinones III. I (R1 = R2 = R3 = R5 = H, n = 3) had an in vitro antihistaminic activity IC50 of 0.018 μg/mL compared to 0.030 μg/mL for oxatomide.
Arzneimittel-Forschung published new progress about Allergy. 52548-84-2 belongs to class imidazoles-derivatives, name is 1-(2-Chloroethyl)-1H-benzo[d]imidazol-2(3H)-one, and the molecular formula is C9H9ClN2O, Quality Control of 52548-84-2.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem