Sobiak, Stanislaw’s team published research in Acta Poloniae Pharmaceutica in 1999-04-30 | CAS: 18874-52-7

Acta Poloniae Pharmaceutica published new progress about Alkylation. 18874-52-7 belongs to class imidazoles-derivatives, name is 5-Bromo-2-methyl-4-nitroimidazole, and the molecular formula is C4H4BrN3O2, Category: imidazoles-derivatives.

Sobiak, Stanislaw published the artcileTetrabutylammonium bromide as a catalyst for reaction of 5(4)-bromo-2-methyl-4(5)-nitroimidazole with phenacyl bromides, Category: imidazoles-derivatives, the main research area is tetrabutylammonium bromide catalyst alkylation bromomethylnitroimidazole; bromomethylnitroimidazole sonication alkylation phenacyl bromide; nitroimiazole bromo alkylation phenacyl bromide; imidazole bromomethylnitro alkylation phenacyl bromide.

Reactions of 5(4)-bromo-2-methyl-4(5)-nitroimidazole with phenacyl bromides BrCH2COC6H4X-4 (X = H, F, Cl, Br, iodo), tetrabutylammonium bromide and sodium bicarbonate under sonication conditions gave mixtures of 4-bromo-5-nitroimidazoles I and 5-bromo-4-nitroimidazoles II in excellent yields of over 85% and, surprisingly, with I/II isomer ratios of 2:1.

Acta Poloniae Pharmaceutica published new progress about Alkylation. 18874-52-7 belongs to class imidazoles-derivatives, name is 5-Bromo-2-methyl-4-nitroimidazole, and the molecular formula is C4H4BrN3O2, Category: imidazoles-derivatives.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem