Saito, Tohru published the artcilePurines. LXIV. Syntheses of 9-methyl-2-azaadenine 1-oxide, its O-methyl derivative, and 1-substituted 5-azidoimidazole-4-carboxamides, Application of 5-Amino-1-methyl-1H-imidazole-4-carboxamide, the main research area is aminoimidazolecarboxamidine diazotization; nucleoside azaadenine; methylazaadenine oxide.
Diazotization of 5-amino-N’-methoxy-1-methylimidazole-4-carboxamidine with NaNO2 in 1N aqueous HCl was found to give the 1-methoxy-2-azaadenine derivative I·HI, which produced 5-azido-1-methylimidazole-4-carbonitrile (II) on treatment with aqueous Na2CO3. The ribosyl analog, obtained by similar diazotization, was utilized for the synthesis of 5-azido-1-β-D-ribofuranosylimidazole-4-carboxamideIII, a novel AICA riboside analog. On heating in HCONMe2 at 70°C for 10 min, I·HI yielded the 1-N-oxide. Several reactions to transform the functional groups in II were also investigated.
Chemical & Pharmaceutical Bulletin published new progress about Diazotization. 21343-04-4 belongs to class imidazoles-derivatives, name is 5-Amino-1-methyl-1H-imidazole-4-carboxamide, and the molecular formula is C5H8N4O, Application of 5-Amino-1-methyl-1H-imidazole-4-carboxamide.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem