Rao, A. K. S. Bhujanga published the artcileA new high-yielding method for the preparation of 2-alkyl- and 1,2-dialkyl-4-nitro-5-bromoimidazoles, Synthetic Route of 18874-52-7, the main research area is alkylnitroimidazole bromination; bromoimidazole alkylnitro; alkylbromonitroimidazole; imidazole alkylnitro bromination.
A new brominating system Br2-DMF-KHCO3 is described for the preparation of the title compounds I (R = H, Et, CH2CH2CN, CH2CH2COMe, CH2CH2CO2Et, CH2CH2CO2H, CH2CO2Et, CH2Ph, CH2C6H4Cl-4, CH2CH2SO2Et, cyclopropylmethyl; R1 = Me, Et). The mild conditions of the reaction allow bromination to be carried out in the presence of acid and base sensitive functionalities in nearly quant. yields.
Journal of Organic Chemistry published new progress about Bromination. 18874-52-7 belongs to class imidazoles-derivatives, name is 5-Bromo-2-methyl-4-nitroimidazole, and the molecular formula is C4H4BrN3O2, Synthetic Route of 18874-52-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem