Fujii, Tozo published the artcilePurines. XX. Synthesis of 1-substituted 5-aminoimidazole-4-carboxamidines and related compounds, Recommanded Product: 5-Amino-1-methyl-1H-imidazole-4-carboxamide, the main research area is imidazolecarboxamidine amino; adenine.
Several 1-substituted 5-aminoimidazole-4-carboxamidines I (R = Me, Et, PhCH2, β-D-ribofuranosyl) were prepared from the corresponding N’-alkoxyamidines (R2 = Me, Et, PhCH2) by catalytic hydrogenolysis. In the hydrogenolysis of II using Raney Ni catalyst, addition of one molar equivalent of HCl accelerated the reaction to give I in acceptable yields. The structures of I were confirmed by cyclization to 9-substituted adenines III and by alk. hydrolysis to 1-substituted derivatives of 5-aminoimidazole-4-carboxamide.
Chemical & Pharmaceutical Bulletin published new progress about Hydrogenolysis. 21343-04-4 belongs to class imidazoles-derivatives, name is 5-Amino-1-methyl-1H-imidazole-4-carboxamide, and the molecular formula is C5H8N4O, Recommanded Product: 5-Amino-1-methyl-1H-imidazole-4-carboxamide.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem