Foldesi, Tamas published the artcileEfficient synthesis of a new compound family, 9-aryl-5H-imidazo[2,1-d][1,2,5]triazepin-6(7H)-ones, SDS of cas: 62457-94-7, the main research area is imidazole aroyl alkylation hydrolysis protection acid ring closure; triazepinone aryl imidazo preparation.
Representatives of a new compound family, 9-aryl-5H-imidazo[2,1-d][1,2,5]triazepin-6(7H)-ones I (Ar = Ph, 4-FC6H4, 4-ClC6H4, 3-ClC6H4, 4-MeOC6H4, 3-CF3C6H4, 4-NO2C6H4, 2-thienyl) have been synthesized. As structural analogs of biol. active 1-aryl-2,3-benzodiazepine-4-ones, these compounds are potential drug candidates in the diseases of the central nervous system. An efficient five-step synthesis starting from imidazole is described here for the preparation of the target compounds Shorter routes have also been studied, however, these attempts failed.
Tetrahedron published new progress about Alkylation. 62457-94-7 belongs to class imidazoles-derivatives, name is (4-Chlorophenyl)(1H-imidazol-2-yl)methanone, and the molecular formula is C10H7ClN2O, SDS of cas: 62457-94-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem