Hand, E. Smakula published the artcileReaction of 3-substituted imidazo[1,2-a]pyridines with bromine(1+) and the alleged 5-bromo-substituted product, Synthetic Route of 5857-47-6, the main research area is bromosuccinimide reaction imidazopyridine.
The reaction of 3-methylimidazo[1,2-a]pyridine with N-bromosuccinimide (I) gave products formed by apparent nucleophilic substitution at the 2-position. I in CHCl3 gave II and III, while I in CCl4 or Br2 in CHCl3 gave II exclusively. Mechanisms and differences in product formation are discussed; evidence is presented that the previously reported I product was in fact 3-bromo-5-methylimidazo[1,2-a]pyridine, rather than the alleged 5-bromo-3-Me derivative IV. IV was prepared by diazotization of 5-amino-3-methylimidazo[1,2-a]pyridine in the presence of HBr and by condensation of MeCHBrCHO (or its acetal) with 2-amino-6-bromopyridine.
Journal of Organic Chemistry published new progress about Reaction mechanism. 5857-47-6 belongs to class imidazoles-derivatives, name is 3-Bromo-5-methylimidazo[1,2-a]pyridine, and the molecular formula is C8H7BrN2, Synthetic Route of 5857-47-6.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem