Garuti, Laura’s team published research in Bioorganic & Medicinal Chemistry Letters in 2002-10-07 | CAS: 5805-53-8

Bioorganic & Medicinal Chemistry Letters published new progress about Antitumor agents. 5805-53-8 belongs to class imidazoles-derivatives, name is Methyl 1H-benzo[d]imidazole-2-carboxylate, and the molecular formula is C9H8N2O2, Recommanded Product: Methyl 1H-benzo[d]imidazole-2-carboxylate.

Garuti, Laura published the artcileSynthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles, Recommanded Product: Methyl 1H-benzo[d]imidazole-2-carboxylate, the main research area is benzimidazolyl sulfone antiviral antiproliferative preparation.

Some benzimidazolyl sulfones were synthesized and evaluated for their antiviral and antiproliferative properties. I (R = CHMe2) displayed significant and selective activity against human cytomegalovirus (CMV), I (R = 3-NO2-C6H4) showed activity against varicella zoster virus (VZV). The compounds were further evaluated for inhibitory effect on the proliferation of murine leukemia cells and human T-lymphocyte cells. Marked cytotoxicity was noted with different derivatives Some structure-activity relationships are discussed.

Bioorganic & Medicinal Chemistry Letters published new progress about Antitumor agents. 5805-53-8 belongs to class imidazoles-derivatives, name is Methyl 1H-benzo[d]imidazole-2-carboxylate, and the molecular formula is C9H8N2O2, Recommanded Product: Methyl 1H-benzo[d]imidazole-2-carboxylate.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem