Sen, A. K. published the artcileSynthetic studies in the purine series: a new synthesis of theobromine and related compounds, Category: imidazoles-derivatives, the main research area is theobromine synthesis; purine alkyl; xanthine alkyl; imidazolecarboxamide amino cyclization carbonate; cyclization aminoimidazolecarboxamide carbonate; rearrangement aminoimidazoecarboxamide.
The imidazoles I (R = Me, H2C:CHCH2, PhCH2, Ph, R1 = CONH2) were methylated with p-MeC6H4SO3Me and the quaternary salts rearranged with NaOH to give the imidazoles II, which were cyclized with (EtO)2CO to give the xanthines III. I (R = PhCH2, R1 = CN) was similarly converted to 4-(benzylamino)-5-cyano-1-methylimidazole. III (R = PhCH2, Ph) were methylated with Me2SO4 to give the 1,7-dimethylxanthines.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about Cyclocondensation reaction. 21343-04-4 belongs to class imidazoles-derivatives, name is 5-Amino-1-methyl-1H-imidazole-4-carboxamide, and the molecular formula is C5H8N4O, Category: imidazoles-derivatives.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem