Revankar, Ganapathi R.; Robins, Roland K. published an article in 1975, the title of the article was Synthesis and biological activity of some nucleosides resembling guanosine: imidazo[1,2-a]pyrimidine nucleosides.Quality Control of 7-Chloroimidazo[1,2-a]pyrimidin-5(1H)-one And the article contains the following content:
Refluxing di-Et malonate in NaOEt with 2-aminoimidazole hemisulfate gave 49.6% 5,7-dihydroxyimidazo[1,2-a]pyrimidine, which was chlorinated with POCl3 and treated with 5% aqueous NaOH to give I. Refluxing I with NH(SiMe3)2 and (NH4)2SO4 followed by addition of tetra-O-acetyl-β-D-ribofuranose and deacetylation gave II (R = Cl) (III). Amination of III with NH3 in MeOH at 100° gave 46% II (R = NH2) which showed no in vitro antiviral activity with the RNA and DNA virus tested. The experimental process involved the reaction of 7-Chloroimidazo[1,2-a]pyrimidin-5(1H)-one(cas: 57473-33-3).Quality Control of 7-Chloroimidazo[1,2-a]pyrimidin-5(1H)-one
The Article related to imidazopyrimidine nucleoside, ribofuranosylimidazopyrimidine virucide, Carbohydrates: Nucleosides, Nucleotides and other aspects.Quality Control of 7-Chloroimidazo[1,2-a]pyrimidin-5(1H)-one
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem