Pozharskii, A. F.; Zvezdina, E. A.; Simonov, A. M. published an article in 1966, the title of the article was Synthesis of 2-nitrobenzimidazole (benzazomycin).Recommanded Product: 5709-67-1 And the article contains the following content:
Reaction of 1-benzyl-2-aminobenzimidazole with 4 g. at. Na in liquid NH3 gave 43% 2-nitrobenzimidazole, decomposed at 258°, and 55% 2,2′-azobenzimidazole (I), red-orange, m. above 350°. With 2 g. atoms Na the reaction gave 32% azo compound and 60% 2-aminobenzimidazole, m. 226.5°. When air is totally excluded, the latter is formed in 78% yield as the sole product. The di-Na derivative of aminobenzimidazole is very easily attacked by air to form the above oxidation products, both of which gave the amino derivative after reduction with Sn-HCl. The nitro derivative was devoid of basic properties and was acidic as it readily formed a Na salt which was easily alkylated in the 1-position. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Recommanded Product: 5709-67-1
2-Nitro-1H-benzo[d]imidazole(cas:5709-67-1) belongs to imidazoles. It is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Recommanded Product: 5709-67-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem