On March 13, 1967, Pozharskii, A F.; Zvezdina, E. A.; Simonov, A. M. published a patent.Quality Control of 2-Nitro-1H-benzo[d]imidazole The title of the patent was Simultaneous preparation of 2-nitrobenzimidazole and 2,2′-azobenzimidazole. And the patent contained the following:
1-Benzyl-2-aminobenzimidazole is treated with an excess of Na in liquid NH3 at -70° followed by separation of 2,2′-azobenzimidazole by acidifying with concentrated HCl, filtrating, acidifying the filtrate, and purifying the product. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Quality Control of 2-Nitro-1H-benzo[d]imidazole
2-Nitro-1H-benzo[d]imidazole(cas:5709-67-1) belongs to imidazoles. It is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Quality Control of 2-Nitro-1H-benzo[d]imidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem