On September 17, 2021, Mathur, Lavina; Jung, Sunhee; Jang, Cholsoon; Lee, Gina published an article.Safety of N-Methyl-7H-purin-6-amine The title of the article was Quantitative analysis of m6A RNA modification by LC-MS. And the article contained the following:
N6-adenosine methylation (m6A) of mRNA (mRNA) plays key regulatory roles in gene expression. Accurate measurement of m6A levels is thus critical to understand its dynamic changes in various biol. settings. Here, we provide a protocol to quantitate the levels of adenosine and m6A in cellular mRNAs. Using nuclease and phosphatase, we digest mRNA into nucleosides, which are subsequently quantified using liquid chromatog. mass spectrometry. For complete details on the use and execution of this protocol, please refer to Cho et al. (2021). The experimental process involved the reaction of N-Methyl-7H-purin-6-amine(cas: 443-72-1).Safety of N-Methyl-7H-purin-6-amine
The Article related to adenine: analogs & derivatives, adenine: analysis, adenine: chemistry, adenosine: analogs & derivatives, adenosine: chemistry, adenosine: metabolism, biochemical phenomena, chromatography, liquid: methods, methylation, nucleosides: analysis, rna: chemistry, rna, messenger: chemistry, rna and other aspects.Safety of N-Methyl-7H-purin-6-amine
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem