On December 31, 2022, Li, Xuwen; Guo, Shiyuan; Cui, Yan; Zhang, Zijian; Luo, Xinlong; Angelova, Margarita T.; Landweber, Laura F.; Wang, Yinsheng; Wu, Tao P. published an article.Synthetic Route of 443-72-1 The title of the article was NT-seq: a chemical-based sequencing method for genomic methylome profiling. And the article contained the following:
Abstract: DNA methylation plays vital roles in both prokaryotes and eukaryotes. There are three forms of DNA methylation in prokaryotes: N6-methyladenine (6mA), N4-methylcytosine (4mC), and 5-methylcytosine (5mC). Although many sequencing methods have been developed to sequence specific types of methylation, few technologies can be used for efficiently mapping multiple types of methylation. Here, we present NT-seq for mapping all three types of methylation simultaneously. NT-seq reliably detects all known methylation motifs in two bacterial genomes and can be used for identifying de novo methylation motifs. NT-seq provides a simple and efficient solution for detecting multiple types of DNA methylation. The experimental process involved the reaction of N-Methyl-7H-purin-6-amine(cas: 443-72-1).Synthetic Route of 443-72-1
The Article related to escherichia helicobacter nt seq genome methylome dna methylation, dna methylation, next-generation sequencing, whole-genome epigenetic profiling, Biochemical Genetics: Methods and other aspects.Synthetic Route of 443-72-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem