On January 8, 1966, Lebedev, O. V.; Epishina, L. V.; Sevost’yanova, V. V.; Novikova, T. S.; Khmel’nitskii, L. I.; Novikov, S. S.; Prikhod’ko, A. S. published a patent.Application In Synthesis of 2-Nitro-1H-benzo[d]imidazole The title of the patent was 2-Nitroimidazoles. And the patent contained the following:
The title compounds are prepared by treating 2-amino derivatives of imidazole with an aqueous solution of Cu(NO2)2 and NaNO2 at a temperature of ∼60°. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Application In Synthesis of 2-Nitro-1H-benzo[d]imidazole
2-Nitro-1H-benzo[d]imidazole(cas:5709-67-1) belongs to imidazoles. It is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Application In Synthesis of 2-Nitro-1H-benzo[d]imidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem