On May 12, 2016, Cook, James H., II; Zusi, F. Christopher; Hill, Matthew D. published a patent.Application In Synthesis of 4-Bromo-1H-benzo[d]imidazol-2(3H)-one The title of the patent was Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands. And the patent contained the following:
The invention relates to preparation of spiro quinuclidine oxazoloazole derivatives of formula I wherein X and R are as defined in the disclosure, which bind to the nicotinic α7 receptor and may be useful for the treatment of disorders of the central nervous system. The experimental process involved the reaction of 4-Bromo-1H-benzo[d]imidazol-2(3H)-one(cas: 40644-16-4).Application In Synthesis of 4-Bromo-1H-benzo[d]imidazol-2(3H)-one
The Article related to spiro quinuclidine oxazoloazole preparation alpha7 nicotinic acetylcholine receptor ligand, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.Application In Synthesis of 4-Bromo-1H-benzo[d]imidazol-2(3H)-one
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem