On April 30, 2014, Zuo, Hui; Ma, Liangxiu published an article.Formula: C17H19N3O2S The title of the article was Study on green synthesis of omeprazole. And the article contained the following:
The aim is to study green synthesis of omeprazole. 4-Anisidine was treated via acetylation, nitration, hydrolysis, reduction and cyclization for synthesis of intermediate of 2-mercapto-5-methoxy-1H-benzimidazole. 2-Hydroxymethyl-3, 5-dimethyl-4-methoxy-pyridine was treated via sulfuryl chloride chlorination treatment to directly synthesize with benzimidazole to obtain intermediate of thioether without separation, and synthesis of omeprazole was achieved by catalytic oxidation The experimental process involved the reaction of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(cas: 73590-85-9).Formula: C17H19N3O2S
The Article related to omeprazole green synthesis economic environment selective oxidation, Pharmacology: Effects Of Gastrointestinal and Respiratory Drugs and other aspects.Formula: C17H19N3O2S
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem