On January 12, 1978, Staehle, Helmut; Koeppe, Herbert; Kummer, Werner; Hoefke, Wolfgang published a patent.Product Details of 65896-14-2 The title of the patent was 2-Bromo-6-fluoro-N-2-imidazolidinylideneaniline. And the patent contained the following:
The title compound (I) and its pharmaceutically acceptable salts were prepared by the cyclization of 2,6-FBrC6H3NHC(SR):NH.HX (II; R = alkyl, X = halogen) with H2NCH2CH2NH2. Thus, II (R = Me, X = iodo) was refluxed with H2NCH2CH2NH2 in BuOH and the mixture treated with HCl to give 56.3% I HCl, which has antihypertensive activity comparable to that of clonidine, with fewer side effects, e.g., inhibition of gastric juice secretion. The experimental process involved the reaction of N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride(cas: 65896-14-2).Product Details of 65896-14-2
The Article related to antihypertensive phenyliminoimidazolidine, phenyliminoimidazolidine, imidazolidine phenylimino, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Product Details of 65896-14-2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem