On March 6, 1973, Robison, Michael Mullen; Finch, Neville published a patent.Product Details of 41010-50-8 The title of the patent was 1-(Aminoalkyl)-2,3-dihydroimidazo[4,5-b]pyridines. And the patent contained the following:
About 15 title compounds (I; R = cyclohexyl, PhCH2, Ph, p-FC6H4, etc.; R1 = MeN, 4-methyl-1-piperazinyl; X = O, S; n = 2,3) were prepared Thus, 2-chloro-3-nitropyridine was treated with PhNH2 and the product hydrogenated (PdC ) to give 3-amino-2-(phenylamino) pyridine, which was treated with 1,1′-carbonyldiimidazole to give 2-oxo-3-phenyl-2,3- dihydroimidazo[4,5-b]pyridine followed by treatment with Me2NCH2- CH2Cl to give I (R = Ph, R1 = Me2N, X = O, n = 2) isolated as the dicyclohexylsulfamate salt. I were intidepressant at 2.5-100 mg/kg/day in higher animals. The experimental process involved the reaction of 3-Phenyl-1H-imidazo[4,5-b]pyridin-2(3H)-one(cas: 41010-50-8).Product Details of 41010-50-8
The Article related to imidazopyridine aminopropyl phenyl antidepressant, antidepressant aminopropylimidazopyridine, pyridine nitro chloro aniline addition, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Product Details of 41010-50-8
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem