On December 16, 1976, Clark, Robert Long; Pessolano, Arsenio A.; Shen, Tsung-Ying published a patent.HPLC of Formula: 41010-50-8 The title of the patent was 1,3-Dihydroimidazo[4,5-b]pyridin-2-ones and thiones. And the patent contained the following:
Imidazopyridinones and thiones I [R = e.g. H, Pr, H2C:CHCH2, Me, PhCH2; R1 = e.g. Ph, 2,4-(MeO)2C6H3, 2,4-Me2C6H3, 3,4-(OCH2O)C6H3, 2-BrC6H4, 3-FC6H4, 2-methyl-6-pyridinyl, 1,3-dihydro-5-isobenzofuranyl; R2 = e.g. H, 6-Me, 6-NO2, 6-NH2; X = O, S], useful as analgesics, antipyretics and inflammation inhibitors (no data), are prepared by reaction of 2-chloro-3-nitropyridine (II) with an aniline, reduction of the resulting 2-anilino-3-nitropyridine to the 3-amino-2-anilinopyridine and cyclocondensation with COCl2 or CSCl2, for example. Thus, reaction of II with 3,4-methylenedioxyaniline gives 2-[3,4-(methylenedioxy)anilino]-3-nitropyridine, which is reduced and cyclocondensed with COCl2 to give I [R = R2 = H, R1 = 3,4-(OCH2O)C6H3, X = O]. The experimental process involved the reaction of 3-Phenyl-1H-imidazo[4,5-b]pyridin-2(3H)-one(cas: 41010-50-8).HPLC of Formula: 41010-50-8
The Article related to imidazopyridinone, imidazopyridinethione, analgesic imidazopyridinone, antipyretic imidazopyridinone, antiinflammatory imidazopyridinone, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.HPLC of Formula: 41010-50-8
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem