On May 20, 2014, Sun, Li-min; Jiang, Ying-yan; Li, Dong-yue; Zhou, Li-ming; Zheng, De-qiang published an article.Application of 73590-85-9 The title of the article was Improvement of synthesis process of esomeprazole magnesium. And the article contained the following:
Synthesis process of esomeprazole magnesium was improved. With 2-mercapto-5-methoxybenzimidazole and 2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine as starting materials, esomeprazole magnesium was synthesized by condensation, asym. oxidation and reaction with magnesium sulfate. The overall yield of esomeprazole magnesium was 67.8%. The improved synthesis process of esomeprazole magnesium can be simple, easily controlled, cost-saving and can provide the product with high purity, and suitable for the industrial production of esomeprazole magnesium. The experimental process involved the reaction of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(cas: 73590-85-9).Application of 73590-85-9
The Article related to esomeprazole magnesium proton pump inhibitor synthesis, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Application of 73590-85-9
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem