On February 28, 2009, Hao, Linghua; Li, Wei; Wei, Jinzhao; Chen, Shuai; Wu, Song published an article.COA of Formula: C17H19N3O2S The title of the article was Preparation of two impurities of omeprazole. And the article contained the following:
To perform the quality control of omeprazole, two impurities of omeprazole 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole were prepared via condensation and oxidation from 5-methoxy-2-benzimidazolethiol and 2-chloromethyl-3,5-dimethyl-4-methoxypyridine. Their structures were confirmed by 1HNMR and MS. The experimental process involved the reaction of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(cas: 73590-85-9).COA of Formula: C17H19N3O2S
The Article related to omeprazole impurity synthesis, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.COA of Formula: C17H19N3O2S
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem