On March 26, 2015, Duggan, Karen Annette published a patent.Electric Literature of 40644-16-4 The title of the patent was Preparation of biphenyl propanamide compounds for the treatment of hypertension and/or fibrosis. And the patent contained the following:
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis. The invention relates to novel terphenyl compounds of formula I [wherein A is selected from (un)substituted Ph, pyridinyl, indazolyl, etc.] or stereoisomers or pharmaceutically acceptable salts thereof, which are claimed and exemplified. II was prepared via a multistep procedure (preparation given). Antihypertensive activity of compounds of formula I was evaluated in spontaneously hypertensive rats on a high salt diet following 4 wks of therapy (data given). The experimental process involved the reaction of 4-Bromo-1H-benzo[d]imidazol-2(3H)-one(cas: 40644-16-4).Electric Literature of 40644-16-4
The Article related to biphenyl propanamide compound preparation hypertension fibrosis, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Electric Literature of 40644-16-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem