Dai, Wen; Li, Guosong; Wang, Lianyue; Chen, Bo; Shang, Sensen; Lv, Ying; Gao, Shuang published an article in 2014, the title of the article was Enantioselective oxidation of sulfides with H2O2 catalyzed by a pre-formed manganese complex.Safety of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole And the article contains the following content:
A variety of sulfide substrates e.g., aryl alkyl, aryl benzyl, cyclic sulfides were oxidized to form their chiral sulfoxides in high yields (up to 95%) and excellent enantioselectivities (>99% ee) in presence of H2O2, pre-formed Mn complex and catalytic amount of adamantoic acid in CH3CN/isopropanol. This synthetic process was environment friendly and the practical utility of the method was demonstrated by the synthesis of esomeprazole and albendazole sulfoxide (ABZO). The experimental process involved the reaction of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(cas: 73590-85-9).Safety of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
The Article related to sulfide manganese complex carboxylic acid catalyst enantioselective oxidation, sulfoxide preparation green chem, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Sulfoxides and Sulfones and other aspects.Safety of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem