Imidazole based anticancer drug find applications in cancer chemotherapy. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Application In Synthesis of 1739-84-0.
Zhao, Shizhen;Yang, Hongkun;Dong, Genlai;Wang, Dong;Russell, Thomas P. research published 《 Fully Biobased Elastomer Composites with Mechanically Robust, Reprocessable, and Biocompatible Properties》, the research content is summarized as follows. It is of importance, though difficult, to integrate reinforcement, functionalization and recyclability into elastomeric materials. Here we describe a biomass-derived epoxidized natural rubber (ENR) crosslinked with dynamic covalent bonds and reinforced with functional carboxymethyl chitosan (CMCS). The ENR/CMCS composites show enhanced mech. properties and thermal stability, due to the uniform dispersion of the CMCS fillers and strong interfacial interaction between the ENR matrix and fillers. These crosslinked rubbers can undergo topol. network rearrangements through dynamic exchange reactions, endowing the materials with reprocessability and recyclability. Due to the biol. derived and green features of the both polymeric matrix and filler, the fully biobased ENR/CMCS composites also show excellent biocompatibility, which will expand their application in the field of biomaterials.
Application In Synthesis of 1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem