Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Computed Properties of 10111-08-7.
Yuan, Hui;Wu, Yuanfeng;Pan, Xiaomei;Gao, Lijing;Xiao, Guomin research published 《 Pyridyl Ionic Liquid Functionalized ZIF-90 for Catalytic Conversion of CO2 into Cyclic Carbonates》, the research content is summarized as follows. The aim of this work was to study the enchanted catalytic activity of 3 ionic liquids functionalized ZIF-90 for CO2 cycloaddition Characterizations such as XRD, FTIR, SEM, XPS, BET, TG and CO2/NH3-TPD were adopted to systematically study the structure and properties of functionalized catalysts. When functionalized by [1-aminoethyl-pyridinium]Br (ZIF-90-IL-1), ZIF-90 possesses the highest catalytic activity among the 3 catalysts, which was consistent with the results of CO2/NH3-TPD characterizations. The reaction was carried out under the conditions of a catalyst addition amount of 1.0%, an initial pressure of 25 bar and a temperature of 90° and 96.27% of propylene oxide (PO) conversion and 94.51% of propylene carbonate (PC) yield were obtained when the reaction was lasted to 8 h. ZIF-90-IL-1 was used in the coupling reaction of various epoxides with CO2 under the same reaction conditions, and when allyl-glycidyl ether (AGE) was used as a substrate, the yield was the highest. One-pot catalytic conversion of CO2 into cyclic carbonate over pyridyl ionic liquid functionalized ZIF-90.[graphic not available: see fulltext].
Computed Properties of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem