Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Product Details of C5H8N2.
Xing, Yi;Geng, Kang;Chu, Xiaomeng;Wang, Chenyi;Liu, Lei;Li, Nanwen research published 《 Chemically stable anion exchange membranes based on C2-Protected imidazolium cations for vanadium flow battery》, the research content is summarized as follows. Imidazolium-based anion exchange membranes (AEMs) are attractive as the separator for vanadium redox flow battery (VFB) application. However, the lack of fundamental understanding of the correlations between imidazolium chem. structure and their phys. properties as well as cell performance constraints the design of advanced AEMs in VFBs. In this work, by designing the “clickable” imidazolium compounds from C2-Me or C2-Ph substituted imidazolium to C2-Ph substituted benzimidazolium, a series of PSf-based AEMs having pendant C2-protected imidazolium derivatives were prepared by efficient CuAAC reaction to explore how the nature of C2 substitution affected the electrochem. property of AEMs and the resulting VFB performance. Interestingly, PSf-MIm with C2-Me protected imidazolium group showed lowest area resistance (0.3 Ω cm2, IEC = 1.66 meq./g) in 3 M H2SO4 aqueous solution but unfavorable vanadium permeability due to its highest swelling ratio. The introduction of bulky C2-Ph substituted benzimidazolium led to the distinct microphase separation in PSf-PhBIm membrane, and thus reduced water uptake, high vanadium selectivity, and comparable conductivity were observed As a result, the single VFB with PSf-MIm-1.2 membrane exhibited better electrochem. performance with a coulombic efficiency (CE) of 97.0%, and an energy efficiency (EE) of 82.4% at a c.d. of 120 mA/cm2, higher than those of Nafion N115 membrane (EE = 75.5%) and unsubstituted imidazolium-based AEMs (EE = 80.6%). More importantly, both ex situ stability testing in 1.5 M (VO2)2SO4/3 M H2SO4 solution for 90 days and in situ cycling performance at a c.d. of 120 mA/cm2 demonstrated that the chem. structure of C2-substituted imidazolium based AEMs remained intact after stability tests as confirmed by NMR anal., while significant degradation was found for unsubstituted PSf-Im membrane via possible nucleophilic addition mechanism. Therefore, the VFB with PSf-MIm membrane showed the best long-term durability with only 34.1% loss in EE for 3638 h of operating (4800 cycles). This work not only fills the knowledge gap on the structure-property relationship of imidazolium-based AEMs for VFB application, but also gives us new directions to design stable AEMs for durable VFBs.
Product Details of C5H8N2, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem